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But, some might get migraine headaches later

Besides, as it reacts with SUMO1-PA/SUMO3-PA probes, suggesting it to be active as exo-isopeptidase acting at the distal end of SUMO2/3 chains terminated by SUMO2/3 or SUMO1

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This is followed by loss of nigrostriatal dopaminergic neurons, with patients exhibiting manifestations such as depression, sleep disturbances, and cognitive dysfunction [22]

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