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Kobalava, Z

[DOI] [PubMed] [Google Scholar] Jang Y.-J

The future remains fraught with obstacles, including antigen identification challenges, intracellular transport impediments, the complexity of metallo-drug conjugation, and the difficulty of large-scale manufacturing for global health deployment

Structure-activity relationship studies toward the discovery of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (dasatinib, BMS-354825) as a potent pan-Src kinase inhibitor