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Elevated circulating TMAO levels resulted in endothelial dysfunction in elderly rats, which was reversed by DMB treatment for 8 weeks (Li et al., 2017)

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10.1038/s41419-020-03020-9 56 IttnerL

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The pooled RR for sICH was 1.65 (95% CI: 1.212.23, p = 0.003), indicating a significantly higher risk of sICH in the EVT group

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