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Hu BJ, Hu YN, Lin S, Ma WJ, Li XR

When immune cells, particularly macrophages and neutrophils, battle perceived threats, they utilize a process called the "respiratory burst" to release large quantities of reactive oxygen species (ROS) designed to destroy pathogens

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The stability of a protein disulfide bond is determined by its intrinsic stability, K eq , plus the ratio of the concentrations of GSH and GSSG: Only very stable protein disulfide bonds, with large values of K eq , could be populated in the cytosol