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Glyceraldehyde-3-phosphate dehydrogenase (G3PD) inactivation was more exaggerated in the older lenses, diminishing ATP production and having a direct impact on lens transparency

On the contrary, the up-regulated genes by overexpression of METTL7A were involved in blastocyst formation at 8-cell stage, tissue development in ICM cells, and voltage- gated potassium and cation channel activities in TE cells, respectively (Figure 2G-I)

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AR desensitization also serves as a compensatory mechanism, which may disrupt cardiac function and promote arrhythmias (Ho et al., 2010)

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