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In rat studies, the peptide produced a 64.5% reduction in wound size over 13 days, compared to 45.6% for vehicle-treated and 28.2% for untreated controls

Its anti-inflammatory mechanisms include reducing TNF-alpha production, downregulating NF-kB activation, and decreasing oxidative stress through enhanced antioxidant enzyme activity

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Optic Nerve Atrophy: Use with caution in patients with Leber's diseasea type of hereditary optic nerve atrophyas it may worsen the condition

Clin J Am Soc Nephrol