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Further research has revealed that KLF2 can bind to the promoter of GPX4 in ccRCC, leading to the downregulation of GPX4 expression, which protects ccRCC cells from ferroptosis, thus promoting tumor cell metastasis (255)

"The Gordon Wilson Lecture

Ikeda and Taniguchi, 2005

The primary bactericidal role of neutrophils is accomplished via phagocytosis and the creation of neutrophil extracellular traps (NETs), which are composed of degraded chromatin and granular proteins from within the cell, triggered by various stimuli