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80 However, the knockout of GPX4 alone is insufficient to induce ferroptosis, indicating the presence of compensatory pathways

Cell 33 , pe7 (2022)

Genome Res 19(1):92105 Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, Noch E et al (2002) Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

Additionally, other antiviral medications, such as molnupiravir and Paxlovid (combination of nirmatrelvir and ritonavir), were evaluated and authorized for emergency use in the treatment of COVID-19 [66,67,68]

The severe conditions, including SIRS or sepsis, can consume the Se content of leukocytes, resulting in lower Se levels in these patients [35]