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The other authors declare no competing interests

Folate must be checked alongside B12, and folate deficiency should never be treated in isolation when B12 is low, because doing so can mask the anaemia while neurological damage progresses

Higher quality products with third-party testing and certificates of analysis generally cost more but provide better assurance of purity and potency

By inhibiting NNMT, the body maintains higher NAD levels, which in turn activate SIRT1, a longevity-associated gene, which may improve mitochondrial activity, fat oxidation, insulin sensitivity, and by overall energy balance

No effects on glucose tolerance, lipid profiles, or liver or kidney function were observed