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Gopukumar et al

High levels of serum prolactin protect against diabetic retinopathy by increasing ocular vasoinhibins

Its clinical significance has been extensively demonstrated in chronic heart failure, particularly heart failure with HFpEF, where elevated serum galectin-3 levels predict new-onset disease, adverse outcomes including all-cause death and cardiovascular death, and correlate with the severity of left ventricular diastolic dysfunction and cardiac structural abnormalities (134, 135)

CCT: cerebral cortex Lutein is popular for its benefits for cardiovascular health, potentially reducing the risk of coronary artery disease perhaps due to its antioxidant and anti-inflammatory properties

Engineered pigs carrying a gain-of-function NLRP3 homozygous mutation can survive to adulthood and accurately recapitulate human systemic spontaneous inflammatory responses