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In conclusion, GA, as a natural multi-target compound, demonstrates significant clinical value in the prevention and treatment of ASCVD, addressing the current demand for safer and more comprehensive therapeutic strategies

Zhao L, Shou H, Chen L, et al

Crit Care Med 24(3):392397 Fowler AA 3rd, Syed AA, Knowlson S, Sculthorpe R, Farthing D, DeWilde C, Farthing CA, Larus TL, Martin E, Brophy DF, Gupta S, Fisher BJ, Natarajan R (2014) Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis

Additionally, methods such as Prussian blue staining and ICP-MS assays revealed that ALA supplementation reduced iron accumulation in both cell lines (Fig