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Description

The class III PI3K complex, composed of Vps34, Beclin-1, p150, and Atg14L, initiates autophagosome formation by producing PI3P [16]

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doi:10.1016/j.jcm.2012.11.001 [PubMed][CrossRef] 133

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In addition, JHU083, an inhibitor of glutamine metabolism, has been observed to increase CD8 T cell and CD4 Th1 cell infiltration, thereby enhancing the efficacy of PD-1 blockers

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