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Maxillomandibular advancement surgery is part of Phase II surgery that may be considered if the patient does not respond (Qureshi, 2003)

It promotes lymphatic fluid circulation, facilitating the rapid release of degraded fat cells, effectively reducing swelling and cellulite

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Compared to a diet rich in animal-based proteins and fats, a high-fiber diet particularly the Mediterranean diet, which enhances butyrate production and inhibits histone deacetylase (HDAC) activity through epigenetic mechanisms, thus preventing CRC cells proliferation