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Omaveloxolone functions by inhibiting the Keap1-mediated degradation of Nrf2, thereby facilitating its nuclear translocation and the subsequent transcription of ARE-dependent genes

It is estimated that influenza has resulted in between 9 million and 45 million illnesses, 140,000 and 810,000 hospitalizations, and 12,000 and 61,000 deaths in the United States annually since 2010 (2)

In contrast to previous studies, high cholesterol in late life was linked with a decreased risk for dementia (Mielke et al., 2005)

However, to date, only a few studies have been published to highlight Grx2s potential roles in humans

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