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Description

The reported K D values should therefore be interpreted cautiously until the experimental details are clarified or independently reproduced

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When serum B12 results are equivocal or clinical suspicion remains high despite normal B12 levels, additional tests may be requested: Methylmalonic acid (MMA) : Elevated levels indicate functional B12 deficiency at the cellular level, though availability may be limited in primary care and levels can be elevated in renal impairment Homocysteine : Also elevated in B12 deficiency, though less specific and also affected by renal function Intrinsic factor antibodies : To investigate pernicious anaemia, the most common cause of B12 deficiency in the UK Anti-parietal cell antibodies : May be tested if pernicious anaemia is suspected but intrinsic factor antibodies are negative Identifying the underlying cause is crucial for appropriate management

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Several recent reviews outlined various applications of nMS in the IDP field (Testa et al., 2013

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Though B vitamin injections have been used to purportedly treat many maladies, including cancer and fibromyalgia, Cancer.org emphatically states that available scientific evidence does not support claims that any B vitamin is an effective treatment for people who already have cancer

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