The reported K D values should therefore be interpreted cautiously until the experimental details are clarified or independently reproduced
When serum B12 results are equivocal or clinical suspicion remains high despite normal B12 levels, additional tests may be requested: Methylmalonic acid (MMA) : Elevated levels indicate functional B12 deficiency at the cellular level, though availability may be limited in primary care and levels can be elevated in renal impairment Homocysteine : Also elevated in B12 deficiency, though less specific and also affected by renal function Intrinsic factor antibodies : To investigate pernicious anaemia, the most common cause of B12 deficiency in the UK Anti-parietal cell antibodies : May be tested if pernicious anaemia is suspected but intrinsic factor antibodies are negative Identifying the underlying cause is crucial for appropriate management
Several recent reviews outlined various applications of nMS in the IDP field (Testa et al., 2013
Though B vitamin injections have been used to purportedly treat many maladies, including cancer and fibromyalgia, Cancer.org emphatically states that available scientific evidence does not support claims that any B vitamin is an effective treatment for people who already have cancer
For more information on B12 injections, read our blogs here