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doi:10.15252/embj.201695810

Induction of both synaptogenesis and synaptic pruning occur through the release of soluble factors and extracellular matrix molecules, such as TGF-Beta1 (83, 84), Hevin, Glypican-4 and -6, Thrombospondin and SPARC

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However, intense evidences suggest that lipid peroxidation can be the common feature that initiates and propagates the cell death