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On the other hand, large predatory fish (such as swordfish) tend to concentrate pollutants, particularly persistent organic pollutants, heavy metals, and microplastics, due to biomagnification and bioaccumulation

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Patients are often compound heterozygote with a combination that includes at least one novel mutations or VUS

To increase the protein recovery, the pellet from this step was resuspended in a buffer (containing 7 M urea and 2 M thiourea in 0.4 M triethylammonium bicarbonate at pH 8.5), freeze-thawed, vortexed and centrifuged at 15,000 g for 15 min at 20 C

We then examined the network genes in diseased kidney tissue by interrogating RNA sequencing data from cortical kidney tissue from two cohorts with early and advanced DKD