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2 Materials and Methods Data on total DDT (DDTs) and total PCB (PCBs) concentrations in marine organisms were retrieved from the International Council for the Exploration of the Sea (ICES), freely available at the institutions website ( The exhaustive dataset includes organisms that rely exclusively on the sea to feed and others that may eventually feed inland, such as many coastal birds and polar bears

Noble metal nanoparticles mainly exhibit electromagnetic enhancement due to their unique optical property, surface plasmon resonance (SPR)

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By inhibiting KMO, which promotes metabolic flux toward KYNA production, it has been shown in preclinical models to protect mitochondria and reduce neurological damage ( 2.4.3 Microbial metabolites and mitochondrial health Microbial-derived indole metabolites, especially IPA, exhibit significant mitochondrial protection and metabolic regulation effects

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