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The newly generated mitochondria from biogenesis can promote ATP production to meet metabolic demands under physiological (such as exercise and cold) and pathological (such as diabetic ischemic cardiomyopathy and ischemic heart disease) conditions [4]

And they happen for many of the same reasons, including an infection, drug reaction, food reaction, bee sting, or allergic reaction

doi: 10.1182/blood-2017-03-770776 11 WangH-FNingFLiuZ-CWuLLiZ-QQiY-Fet al

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They both consisting of: An extracellular N-terminus that binds the C-terminal part of the incretin analog A seven transmembrane helical domain (TMD) with the a-helices separated by three intracellular loops and three extracellular loops An intracellular C-terminus that is responsible for signaling