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Excessive consumption of high-calorie foods rich in fatty acids and trans fat leads to the accumulation of fatty acids and liposoluble toxins in the testicular environment, affecting spermatogenesis and testosterone production in Leydig cells (67)

Z.Z., J.Q

Notably, HO-1 and mitochondrial ferritin play critical roles in disease progression, and inhibiting their overexpression may represent a novel management strategy for osteoporosis