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doi: 10.3389/fonc.2022.923043 78 TacchiniLBianchiLBernelli-ZazzeraACairoG

Skin sensitization risk assessment is not a highly prescriptive process that should always be followed in the same way (Calvin, 1992)

Oyadomari, S., Koizumi, A., Takeda, K., Gotoh, T., Akira, S., Araki, E., and Mori, M

However, more thorough pharmacokinetic studies should be conducted in order to prove that enhanced in vivo efficacy is resulted by higher extent of the drug delivery into the target tissue