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Meanwhile, knowing the mechanism of GSH-responsive and -exhausting cancer treatment strategies based on metal nanomedicines is vital for selecting an optimized approach to GSH consumption and improving the efficiency of cancer therapy

In addition, curcumin exerts tumor suppressive effect via inhibition of E3 ubiquitin ligase NEDD4 (neural precursor cell-expressed developmentally downregulated gene 4) oncoprotein in glioma cells [114]

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We measured the in vitro activities of major malate metabolism enzyme as NADP-ME which appeared to be significantly varied all through the treatments

Acute glucose fluctuation impacts microglial activity, leading to inflammatory activation or self-degradation