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doi: 10.3389/fphar.2019.01102 Received 07 May 2019 Accepted 26 August 2019 Published 20 September 2019 Volume 10 - 2019 Edited by Deslypere Jean Paul, Besins Healthcare, Thailand Reviewed by Pooja Dhupkar, University of Texas MD Anderson Cancer Center, United States

Misaligned expectations are the most common reason patients discontinue prematurely

The addicted person feels an inner compulsion to increase doses of psychoactive substances, losing control over their use

The 18 peptides with the largest log10[p adj ] values are shown in Table 2, with linear fold-changes from 1.5 to 3.3 (see also Fig