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Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia

This suggests that these pathways act at the level of both CBS enzymatic activity and expression level

doi: 10.1016/j.immuni.2012.10.020

These selected B7 variants can then be subjected to new rounds of reassembly (optionally in combination with other directed evolution methods described herein) and selection, and/or they can be further analyzed using functional assays as described below