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doi: 10.1126/science.288.5472.1765 254 WoolfC

Syringaresinol is a natural plant-derived polyphenolic compound, triptolide as a complex triepoxide diterpene natural product, similar protective effects have been observed in diabetic kidney-related studies [71, 72]

Additionally, TFR1, acyl-CoA synthetase family member 2 (ACSF2), and heme oxygenase-1 (HO-1) expression were significantly upregulated, leading to increased ferroptosis in the optic nerves of locally demyelinated MS mice