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Diabetes patients face particular vulnerability due to metformin therapy, which significantly impairs B12 absorption over time

These immunogenic properties are particularly significant in glioblastoma, where ferroptosis-related gene signatures demonstrate strong predictive value for response to PD-1 blockade in recurrent tumors, suggesting an intrinsic synergy between ferroptosis and immune checkpoint inhibition [129]

Mathematically combined half-cell reduction potentials of low-molecular-weight thiols as markers of seed ageing

doi: 10.1016/j.bbadis.2016.11.005 61 MittalMSiddiquiMRTranKReddySPMalikAB

This has been explored by clinical trials, the most notable of which was METAOD005