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10.1038/s41573-020-0068-6 51 MoriyaM.OuC.BodepudiV.JohnsonF.TakeshitaM.GrollmanA

Muscle contractility in spinobulbar muscular atrophy

The activation of TLR4 in monocytes and granulocytes induces a rapid rise in intracellular zinc levels

It also has antioxidant properties, helping to protect cells from damage

In these experiments, it was important to understand that GST itself was causing this hyperactivity, rather than something intrinsic to BCR-ABL (Maru et al, 1996)