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KD, by promoting the use of KBs as an energy source, offers considerable potential for neuroprotection in PD through mechanisms such as enhancing mitochondrial function, reducing oxidative stress, and exerting anti-inflammatory effects

10.1001/jamapsychiatry.2019.1119 315 MelisM.VascellariS.SantoruM

BTZ-induced ER stress suppresses the expression of key myelination-associated genes, including P0 and Krox20, in SCs, thereby disrupting their physiological functions and contributing to the demyelination of peripheral nerve fibers (Shin et al., 2010)

Similarly, in Acinetobacter spp., a Zn metallochaperone supports activity of an enzyme critical for riboflavin synthesis (Nairn et al., 2016)