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Variables that increase the risk of toxicity include the type of LA and dose, site of injection, the patients comorbidities, extremes of age, and small size or limited muscle mass

a neoplasm, or tumor is a neoplastic mass resulting from abnormal uncontrolled cell growth, which can be benign or malignant

USP7 is a deubiquitinating enzyme (DUB) that can alter the degradation rate and cellular localization of specific protein substrates, some of which are of high interest in cancer progression 58

Vitamin C also supports the absorption of iron, while preventing its oxidation [21,22]

If refrigerated, allow the refrigerated solution to reach room temperature before administration