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Altered miRNA profiles have been reported in the cochlea following acoustic trauma, and in tinnitus models induced by other etiologies such as salicylate, suggesting that miRNA dysregulation may contribute to maladaptive responses to peripheral injury (Patel et al., 2013)

In contrast, a meta-analysis of RCTs showed that probiotic supplements did not have a significant effect on the frequency and severity of episodic migraine attacks (214)

Additionally, alcohol use disorder (AUD) imposes a substantial economic burden [5]

Circulation ACC/AHA CLINICAL PRACTICE GUIDELINE 2019 ACC/AHA Guideline on the primary prevention of cardiovascular disease association task force on clinical practice guidelines