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Similarly, the administration of melatonin and vitamin E could exert beneficial effects in preventing the effects of Hcy on plasma antioxidant enzymes, as demonstrated by the impeded decrease of plasma antioxidant enzyme activity in Hcy-treated male rats [217]

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In vitro, a T2 cytokine (IL-13) induced 15LO1 generation of hydroperoxy-phospholipids, which lowered intracellular GSH and increased extracellular GSSG

Activating transcription factor 3 (ATF3), one of the transcription factors involved in regulating ER stress, was responsible for the reduction of LAMP2A expression under the ER stress condition