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MDMs were plated in triplicate into 12-well cell culture plates (Takara Biotechnology (Dalian), Co., Ltd., Dalian, China)

Glucose uptake, through the GLUT family of transporters, serves as a key checkpoint in T cells by affecting T cell fate and orchestrating specialized adaptive immune responses 21,31,32,33

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This work was further supported by the UKs Experimental Arthritis Treatment Centre for Children (supported by Versus Arthritis, Alder Hey Childrens NHS Foundation Trust, the Alder Hey Charity, and the University of Liverpool) and partially carried out at the NIHR Alder Hey Clinical Research Facility