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Melanoma has a much higher case-fatality rate (10-20%) than either SCC or BCC

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In addition to the microbiota itself, intestinal fungi inhibit bacterial colonization by producing alcohol, antibacterial peptides, and some metabolites 145,146

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For example, while low-dose polyphenols stimulate endogenous antioxidant defenses, high concentrations, such as those found in concentrated supplements, can act as potent pro-oxidants, leading to increased oxidative stress and cellular damage 51

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