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showed increased epidermal and dermal thickness, skin hydration, skin elasticity, skin contrast, and collagen I synthesis A trial with 41 women applying GHK-Cu eye cream for three months reported reduced lines and wrinkles, improved skin density, and increased skin thickness, outperforming both placebo and vitamin K cream Comparable studies show wrinkle volume reductions around 60-70%, attributed to enhanced collagen cross-linking and decorin synthesis Key Benefits for Product Claims Formulators can support the following claims when incorporating GHK-Cu: Firmer feel and improved skin firmness Smoother skin texture with reduced wrinkles More even tone and enhanced radiance Improved skin hydration and barrier function Powerful antioxidant protection against environmental stressors and reactive oxygen species Reduction of visible redness Effects are gradual rather than instant, relying on consistent use to deliver meaningful improvements in skin density and overall appearance

& Rosenfield, R

Following incubation of cells for 90 min at 37 C, unbound cells were removed by three washes with DMEM-F12 advanced medium

Glutathione is known as the mother of all antioxidants and is key to immune system function, Higher glutathione levels are associated with enhanced physical health, fewer illnesses, and improved quality of life, Glutathione is directly influential on telomerase activity which is an important biomarker for cell proliferation and life