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DHEA inhibited lung fibroblast proliferation in a laboratory setting as well

7 BogeskiI.KummerowC.Al-AnsaryD.SchwarzE

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Another screening procedure involves use of mammalian cells (CHO, HEK293, Xenopus Oocytes, RBL-2H3, etc.) which are transfected to express the receptor of interest, and which are also transfected with a reporter gene construct that is coupled to activation of the receptor (for example, luciferase or beta-galactosidase behind an appropriate promoter)