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Lutein and Zeaxanthin: Pigments of the Macula Lutein and zeaxanthin are not precursors of vitamin A, but they can naturally accumulate in the eye especially in the macula, the area responsible for sharp central vision

Cell Culture The human colon cancer cell lines HCT116 and SW620, purchased from American Type Culture Collection (Manassas, VA, USA), were cultured in RPMI medium and DMEM/F12 (HyClone, Logan, UT, USA) respectively, supplemented with 10% foetal bovine serum (HyClone) and 1% penicillin and streptomycin

Barrier dysfunction due to unavoidable injuries or allergic responses enhances the release of IL-1, leading to the increased formation of cytokine proteins [183, 184]

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