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2 AbeK.ItoyamaY.SobueG.TsujiS.AokiM.DoyuM.et al (2014)

J Clin Endocrinol Metab 99(8):E1454E1458

DNA is normally tightly packed in structures called nucleosomes, which involve the wrapping of DNA strands around proteins called histones - the tighter the DNA is packed, the more difficult it is for genes to be expressed