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PRMTs can be categorized into three types based on their catalytic activity: Type I PRMTs (PRMT1, PRMT2, PRMT3, PRMT4, PRMT6, and PRMT8), Type II PRMTs (PRMT5 and PRMT9), and Type III PRMTs (PRMT7)

Mukhtar H, Lee IP, Bend JR (1978) Glutathione S-transferase activities in rat and mouse sperm and human semen

HDAC inhibitors can suppress the expression of MMP14 in GBM, and the inhibition of MMP14 helps to reduce tumor angiogenesis, inflammation, cancer cell invasion, and metastasis, thereby promoting tumor radiotherapy resistance