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Cloning of a Neisseria meningitidis gene for L-lactate dehydrogenase (L-LDH): evidence for a second meningococcal L-LDH with different regulation

In vitro binding studies using the three PET ligands in post-mortem tissues also revealed differences in binding properties, including multiple binding sites with varying affinities 375,376

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doi: 10.1038/s41598-023-36092-6 89 SakemuraRHefaziMSieglerELCoxMJLarsonDPHansenMJet al

Dysregulation of inflammatory and immune responses is also evident, often shifting towards a more pro-inflammatory state with altered cytokine profiles [34]