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1 Introduction Cancer, an increasingly prevalent disease internationally, has become one of the principal causes of morbidity and death globally, with serious economic costs to society

Samples were grinded (60 Hz, 3 min)

Images were analysed using a custom-made CellProfiler version 2.1.1 pipeline and KNIME version 2.12.2

Angiotensin II (Ang II), a mature octa peptide serves as the final effector presser component of the pathway formed from the exopeptidase activity of Angiotensin Converting Enzyme (ACE) on carboxy-terminal of Angiotensin I (Ang I)

Needle-free Peptide Administration: Nasal sprays offer a simple method for peptide therapy delivery without the need for needles, injections, or peptide preparation, reducing potential side effects