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Store in the refrigerator (28C / 3646F)

Clinicians typically start patients at the middle ODT dose (5 mg) when switching from low-dose injectables (0.25 to 0.5 mg weekly) and titrate based on response

Only brand with a published clinical trial over 100 participants a 150-day double-blind study of 120 participants showed 93% shedding reduction and a mean increase of 12 hairs per cm

2010 Aug;95(8):1429-32

Site rotation across these regions on a weekly basis is standard practice for all once-weekly subcutaneous peptide administrations, and is particularly important during extended retatrutide dosing studies where repeated injection at a single site can cause localized lipodystrophy or reduced absorption efficiency