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The pathogenesis of NAFLD, the identification of therapeutic targets, and the advancement of drug development have all made steady progress, but there is still no specific therapeutic agent for the treatment of NAFLD/NASH, and no medication has yet been approved for use in the condition (64)

Thermo Fisher Scientific) into the peritoneum of mice recipients before lesion isolation, using a 27-gauge needle (Thermo Fisher Scientific)

Scientific research suggests the approach may have some merit

Similarly, metformin in addition to its antiglycemic and favorable effects in metabolic syndrome also lowers AMPK activity and inhibits mTOR pathway

Combined therapy using traditional pharmacological agents and MSCs might also be an interesting approach for CIPN prevention and treatment [157]