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Moreover, BH4 plays a pivotal role in antioxidant defense and the removal of nitrogen oxides (80)

Recent investigations have revealed a novel role for autophagy in cancer cell death, showing that autophagy can initiate the breakdown of ferritin, consequently triggering ferroptosis (143)

Lapenna D., Glutathione and Glutathionedependent Enzymes: From Biochemistry to Gerontology and Successful Aging, Ageing Research Reviews 92 (2023): 102066

Subsequent studies will need to clearly evaluate the safety and risk associated with more invasive measures that efficiently transduce or treat smaller areas, compared with broader, less-invasive means of distribution associated with limited brain penetrance due to the need to bypass the BBB

However, in the presence of Hg 2+ , the color remains purple due to strong THg 2+ T coordination, enhancing sensitivity and lowering the limit of detection to 100 nM (20 ppb), which is much lower than organic colorimetric systems (Fig