napqi glutathione Paracetamol metabolism pathways and breakdown into Biopharmaceutics and Drug Disposition |
Biopharmaceutics and Drug Disposition Pharmacology Journal Wiley Online Library A) The CID pathways of N acetyl p benzoquinone imine glutathione Download Scientific Diagram Acetaminophen toxicity EMCrit Project Most people don't realise this Paracetamol breaks down into a toxic compound called NAPQI. Your liver neutralizes it using glutathione (your body's defense shield). But when you take it too often 3 Glutathione Rescue Normally, glutathione binds NAPQI and converts it into non toxic byproducts (cysteine + mercapturic acid) that are excreted. Example: Glutathione is your liver's safety net against toxins.
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