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Thus, FRDA is largely a disease of decreased expression levels of FXN in the expansion model, and loss-of-function of FXN in the non-expansion mutations discussed

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Defects in ALDH2 have been linked to increased alcohol-associated cancers (109)

The second one includes biochemical reactions catalyzed by the enzymes GGP, GPP, GDH, and GLDH, which together transform GDP--L-galactose into AsA

A sub-standard solvent introduces unnecessary variables into otherwise controlled research environments