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Description

Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease

The answer depends on what you're trying to achieve and how your body responds

doi: 10.1038/s41598-023-43123-9, 22

SUMOylation regulates the transcriptional activity of NRF2, affects its interaction with other proteins and intracellular localization, and protects NRF2 from ubiquitination-mediated degradation [129]