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Description

These pathways often intersect with the major proteostasis machineries, providing additional layers of regulation

10.1016/B978-0-08-100262-9.00002-1 Bioresorbable Polym

Our results show that both Arg catabolism (via Put) and Gln catabolism (via Glu) are coupled with GAB biosynthesis in T H 17 cells, implicating GAB as a crucial metabolic node and a branch point in amino acid catabolism

In the second step, conjugating enzymes perform addition reactions (e.g., acetyl, methyl, glucuronic acid) on these newly modified, electrophilic substrates