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This suppression manifests as a 45% reduction in cyclic adenosine monophosphate (cAMP) levels and 53% inhibition of protein kinase A (PKA) activity, effectively disrupting the molecular machinery required for normal testicular function ( 3.2 Metabolic enzyme regulation and steroidogenesis EED interference with critical enzymatic pathways responsible for testosterone biosynthesis and xenobiotic detoxification creates profound hormonal imbalances that compromise reproductive function

The starting dose is typically 20 units (20mg)

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Doctors might also need to adjust how much and how often to give it, based on each patients needs