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Conditional knockout of HIF-1 in osteoclasts of mice (Ctsk-cre, HIF-1 flox/flox ) will result in severe condylar deformity during condylar growth, with shortened condylar length and disordered fibrocartilage arrangement

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Cardiovascular complications, including cardiomyopathy and structural cardiac remodelling, appear to represent the most clinically significant outcomes, as comprehensively described by Iliakis and Stamou ( Hepatic toxicity and endocrine disruption further compound the systemic burden of AAS misuse

Astroglial glutamate signaling and uptake in the hippocampus