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It is triggered by the GTPases mitofusin 1 (Mfn1) and mitofusin 2 (Mfn2), located in the OMM

All bond lengths were constraint using the linear constraint solver (LINCS) algorithm 39

J.et al (2010)

Furthermore, tubuloids obtained via urine from cystic fibrosis patients were used to assess treatment efficacy and circumvented the use of an invasive method to obtain patient material (Schutgens et al